Abd-Elnaby, Y. A., ElSayed, I. E., AbdEldaim, M. A., Badr, E. A., Abdelhafez, M. M., & Elmadbouh, I. (2022). Anti-inflammatory and antioxidant effect of Moringa oleifera against bisphenol-A-induced hepatotoxicity. Egyptian Liver Journal, 12, Article 57. https://doi.org/10.1186/s43066-022-00219-7
Algefare, A. I., Alfwuaires, M., Famurewa, A. C., Elsawy, H., & Sedky, A. (2024). Geraniol prevents CCl₄-induced hepatotoxicity via suppression of hepatic oxidative stress, pro-inflammation and apoptosis in rats. Toxicology Reports, 12, 128–134. https://doi.org/10.1016/j.toxrep.2024.01.007
Aly, O., Abouelfadl, D. M., Shaker, O. G., Hegazy, G. A., Fayez, A. M., & Zaki, H. H. (2020). Hepatoprotective effect of Moringa oleifera extract on TNF-α and TGF-β expression in acetaminophen-induced liver fibrosis in rats. Egyptian Journal of Medical Human Genetics, 21, Article 69. https://doi.org/10.1186/s43042-020-00106-z
Asrani, S. K., Devarbhavi, H., Eaton, J., & Kamath, P. S. (2019). Burden of liver diseases in the world. Journal of Hepatology, 70(1), 151–171. https://doi.org/10.1016/j.jhep.2018.09.014
Benzie, I. F. F., & Strain, J. J. (1996). The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": The FRAP assay. Analytical Biochemistry, 239(1), 70–76. https://doi.org/10.1006/abio.1996.0292
Bonferoni, M. C., Gavini, E., Rassu, G., Maestri, M., & Giunchedi, P. (2020). Chitosan nanoparticles for therapy and theranostics of hepatocellular carcinoma (HCC) and liver-targeting. Nanomaterials, 10(5), Article 870. https://doi.org/10.3390/nano10050870
Congyong, S., Wenjing, L., Yingkun, L., Wenwen, D., Adu-Frimpong, M., Huiyun, Z., Qilong, W., Jiangnan, Y., & Ximing, X. (2019). In vitro/in vivo hepatoprotective properties of 1-O-(4-hydroxymethylphenyl)-α-L-rhamnopyranoside from Moringa oleifera seeds against carbon tetrachloride-induced hepatic injury. Food and Chemical Toxicology, 131, Article 110531. https://doi.org/10.1016/j.fct.2019.05.039
Cuadrado, A., Rojo, A. I., Wells, G., Hayes, J. D., Cousin, S. P., Rumsey, W. L., Attucks, O. C., Franklin, S., Levonen, A. L., Kensler, T. W., & Dinkova-Kostova, A. T. (2019). Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases. Nature Reviews Drug Discovery, 18(4), 295–317. https://doi.org/10.1038/s41573-018-0008-x
Esterbauer, H., & Cheeseman, K. H. (1990). Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal. Methods in Enzymology, 186, 407–421. https://doi.org/10.1016/0076-6879(90)86134-H
Fuertes-Agudo, M., Luque-Tévar, M., Cucarella, C., Martín-Sanz, P., & Casado, M. (2023). Advances in understanding the role of NRF2 in liver pathophysiology and its relationship with hepatic-specific cyclooxygenase-2 expression. Antioxidants, 12(8), Article 1491. https://doi.org/10.3390/antiox12081491
Gao, F., Feng, X., & Li, X. (2025). Recent advances in polymeric nanoparticles for the treatment of hepatic diseases. Frontiers in Pharmacology, 16, Article 1528752. https://doi.org/10.3389/fphar.2025.1528752
Guo, J., Lin, Y., Gong, X., Kuang, G., Hu, J., Du, H., Liu, H., Zhang, J., Zhang, L., Wan, J., & Wang, T. (2025). PROM2 exacerbates CCl₄-induced liver fibrosis via NLRP3 inflammasome activation and hepatocyte pyroptosis. Cellular and Molecular Life Sciences, 82(1), Article 403. https://doi.org/10.1007/s00018-025-05920-5
Hammad, S., Ogris, C., Othman, A., Erdoesi, P., Schmidt-Heck, W., Biermayer, I., Helm, B., Gao, Y., Piorońska, W., Holland, C. H., D’Alessandro, L. A., de la Torre, C., Sticht, C., Al Aoua, S., Theis, F. J., Bantel, H., Ebert, M. P., Klingmüller, U., Hengstler, J. G., Dooley, S., & Mueller, N. S. (2023). Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation. Cell Death & Disease, 14, Article 414. https://doi.org/10.1038/s41419-023-05855-4
Heidarpour, F., Mohammadabadi, M. R., Zaidul, I. S. M., Maherani, B., Saari, N., Hamid, A. A., Abas, F., Manap, M. Y. A., & Mozafari, M. R. (2011). Use of prebiotics in oral delivery of bioactive compounds: A nanotechnology perspective. Pharmazie, 66(5), 319–324. https://doi.org/10.1691/ph.2011.0279
Jha, R., & Mayanovic, R. A. (2023). A review of the preparation, characterization, and applications of chitosan nanoparticles in nanomedicine. Nanomaterials, 13(8), Article 1302. https://doi.org/10.3390/nano13081302
Livak, K. J., & Schmittgen, T. D. (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2^(-ΔΔCt) method. Methods, 25(4), 402–408. https://doi.org/10.1006/meth.2001.1262
Mgheer, T. H., Al-Azawi, R. S. A., Mohi, W. Z., & Al-Shukri, H. H. K. (2026). Correlation of ACE (I/D) gene polymorphisms with type 2 diabetes mellitus and post-recovery from Covid-19 in Iraqi patients: A case-control investigation. Agricultural Biotechnology Journal, 18(1), 281–300. https://doi.org/10.22103/jab.2025.26432.1812
Mohammadabadi, M. R., & Mozafari, M. R. (2018). Enhanced efficacy and bioavailability of thymoquinone using nanoliposomal dosage form. Journal of Drug Delivery Science and Technology, 47, 445–453. https://doi.org/10.1016/j.jddst.2018.08.019
Mohammadabadi, M. R., & Mozafari, M. R. (2019). Development of nanoliposome-encapsulated thymoquinone: Evaluation of loading efficiency and particle characterization. Journal of Biopharmaceuticals, 11(4), 39–46.
Mohammadabadi, M. R., El-Tamimy, M., Gianello, R., & Mozafari, M. R. (2009). Supramolecular assemblies of zwitterionic nanoliposome-polynucleotide complexes as gene transfer vectors: Nanolipoplex formulation and in vitro characterization. Journal of Liposome Research, 19(2), 105–115. https://doi.org/10.1080/08982100802547326
Mohammed, A. J., Al-Awadi, H. K., & Al-Shukri, H. H. K. (2025). Synthesis and characterization of Aspartame and Neotame-encapsulated PLGA-TPGS nanoparticles and their modulatory effects on acetylcholinesterase gene expression in male rats. Regulatory Mechanisms in Biosystems, 16(2), Article e25067. https://doi.org/10.15421/0225067
Mortazavi, S. M., Mohammadabadi, M. R., & Mozafari, M. R. (2005). Applications and in vivo behaviour of lipid vesicles. In M. R. Mozafari (Ed.), Nanoliposomes: From fundamentals to recent developments (pp. 67–76). Elsevier.
Omeodu, S. I., Eruotor, H. O., & Akpan, M. U. (2022). Effect of aqueous extract of Moringa oleifera leaves on some serum enzymes of Wistar rats with carbon tetrachloride-induced liver damage. International Journal of Biochemistry Research & Review, 31(4), 17–23. https://doi.org/10.9734/ijbcrr/2022/v31i430315
Pareek, A., Pant, M., Gupta, M. M., Kashania, P., Ratan, Y., Jain, V., Pareek, A., & Chuturgoon, A. A. (2023). Moringa oleifera: An updated comprehensive review of its pharmacological activities, ethnomedicinal, phytopharmaceutical formulation, clinical, phytochemical, and toxicological aspects. International Journal of Molecular Sciences, 24(3), Article 2098. https://doi.org/10.3390/ijms24032098
Pari, L., & Kumar, N. A. (2002). Hepatoprotective activity of Moringa oleifera on antitubercular drug-induced liver damage in rats. Journal of Medicinal Food, 5(3), 171–177. https://doi.org/10.1089/10966200260398206
Peng, M., Fang, F., & Wang, B. (2025). Nanoparticle technologies for liver targeting and their applications in liver diseases. Frontiers in Pharmacology, 16, Article 1661872. https://doi.org/10.3389/fphar.2025.1661872
Rajabimashhadi, Z., Masi, A., Bagheri, S., Mele, C., Colangelo, G., Paladini, F., & Pollini, M. (2025). Development and characterization of chitosan microparticles via ionic gelation for drug delivery. Polymers, 17(19), Article 2603. https://doi.org/10.3390/polym17192603
Singh, D., Arya, P. V., Aggarwal, V. P., & Gupta, R. S. (2014). Evaluation of antioxidant and hepatoprotective activities of Moringa oleifera Lam. leaves in carbon tetrachloride-intoxicated rats. Antioxidants, 3(3), 569–591. https://doi.org/10.3390/antiox3030569
Soto, J. A., Gómez, A. C., Vásquez, M., Barreto, A. N., Molina, K. S., & Zúñiga-González, C. A. (2025). Biological properties of Moringa oleifera: A systematic review of the last decade. F1000Research, 13, Article 1390. https://doi.org/10.12688/f1000research.157194.2
Tao, L., Gu, F., Liu, Y., Yang, M., Wu, X.-Z., Sheng, J., & Tian, Y. (2022). Preparation of antioxidant peptides from Moringa oleifera leaves and their protection against oxidative damage in HepG2 cells. Frontiers in Nutrition, 9, Article 1062671. https://doi.org/10.3389/fnut.2022.1062671
Weiskirchen, R., Weiskirchen, S., & Tacke, F. (2019). Organ and tissue fibrosis: Molecular signals, cellular mechanisms and translational implications. Molecular Aspects of Medicine, 65, 2–15. https://doi.org/10.1016/j.mam.2018.06.003
Zarrabi, A., Alipoor Amro Abadi, M., Khorasani, S., Mohammadabadi, M., Jamshidi, A., Torkaman, S., Taghavi, E., Mozafari, M. R., & Rasti, B. (2020). Nanoliposomes and tocosomes as multifunctional nanocarriers for the encapsulation of nutraceutical and dietary molecules. Molecules, 25(3), Article 638. https://doi.org/10.3390/molecules25030638